PRODUCT REVIEWS & BUYING GUIDES
US EDITION · USD

Blood test

Empirical Health Heart Health Test

Heart-focused blood panel with ApoB and Lp(a) in one lab visit

Our reviews rest on published sources, not hands-on testing. Our method

Porsche also cofounded Superhuman Chambers, which sells hyperbaric chambers · About the author. This is general information, not medical advice, and no clinician has reviewed it.

The verdict

Empirical's Core program is one lab visit with 100+ biomarkers, including ApoB and Lp(a), plus a written report and app access. Its homepage calls the $190 a one-time payment, but its comparison pages print the same price as "$190/year". The $399 Advanced program adds retests and a doctor video visit, and New York and New Jersey add $99.

The trade-off

Its pages disagree on whether $190 is one-time or yearly, and the $399 plan adds retests and a doctor video visit.

At a glanceBlood test

Biomarkers
100+ per Empirical
Key markers
ApoB, Lp(a), ApoA1, hs-CRP, a full lipid panel, HbA1c, glucose…
Programs
Core is $190 for one lab visit with a written report
Add-ons
Fasting insulin +$14, PSA +$19, extended thyroid…
All the details →

Model reviewed: Core program: one lab visit with 100+ biomarkers, a written report and app access, $190. The $399 Advanced program adds retests and a doctor video visit

$190

US price, checked

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  • Returns Empirical's return policy lets you request a refund if you haven't used a test within 30 days of buying it. See conditions
About this price

This is the Core program price on Empirical's homepage and order page, before tax. The homepage labels it a "One-Time Payment" for 100+ biomarkers in a single lab visit, with full access to Empirical Pro. Empirical's comparison pages print the same price as "$190/year", and no page explains the difference. New York and New Jersey add a $99 lab fee, so the Core program is $289 there. The order page lists the Advanced program at $399 for three tests across the year. Add-on panels cost extra. No sale price was shown. Value figures beside the price, such as "$1,450 of medical care", aren't prices Empirical charges.

Where $190 sits among the 12 test prices we checked
$100$200$500

A GOOD FIT FOR

An adult who wants ApoB, Lp(a) and a broad panel from one lab visit, paid out of pocket.

  • You want ApoB, Lp(a) and hs-CRP in one lab visit and will pay out of pocket
  • You live near a Quest location, or a BioReference lab in New York or New Jersey
  • You want an app that tracks results over time and a written report to bring to your own doctor

THINK TWICE IF

  • Anyone who needs insurance to pay, since Empirical says its heart health program is cash pay
  • Anyone under 18, which Empirical's terms bar
  • Anyone who wants a home blood draw, since the pages checked don't mention one
  • Anyone in a state Empirical doesn't serve, since it says only that its medical services cover over 30 states
  • Anyone who wants a refund after the test is used
  • Anyone expecting a diagnosis or a replacement for their own doctor, since Empirical's terms say it isn't a medical group
What still needs checking
  • Whether the $190 Core program renews, since the homepage says one-time and the comparison pages say $190/year
  • How long the included Empirical Pro app access lasts
  • Whether the $399 Advanced program renews after 12 months, since Empirical's changelog first called it a subscription
  • Which states can order, since the FAQ says over 30 and the locations page names 22 and mentions New Jersey
  • Whether the $99 New York and New Jersey lab fee also applies to the Advanced program
  • Which entries make up the 100+ biomarker count, since the homepage list has 93
  • How the urinalysis sample is collected, which the pages checked don't spell out
  • The price of a standalone retest for Core buyers
  • Who reviews a Core report, and how a doctor follows up on an abnormal result
  • Whether the Quest and BioReference labs hold CLIA or CAP status for these tests, which the pages checked don't state
  • Whether a home blood draw is offered, since the pages checked don't mention one
  • Whether Empirical's Medicare ACCESS care program is live, since its page still says spots open in July 2026
  • Whether any regulator has acted against Empirical. A web search found nothing, but FDA, FTC and state databases weren't searched

Is Empirical Health worth it?

It can be worth it if you want ApoB, Lp(a) and a broad panel in one lab visit, paid out of pocket. The Core program costs $190 for 100+ biomarkers, a written report and app access13. A Cochrane review of randomized trials found that general health checks in adults had little or no effect on total mortality11. Those trials tested health checks in general, not Empirical’s panel. The pages checked cite no outcome study of the program itself13.

How much does Empirical Health cost?

The Core program costs $190 before tax, and Empirical’s homepage calls it a one-time payment1. Its comparison pages print the same price as “$190/year” without explaining why, so renewal is unclear10. New York and New Jersey add a $99 lab fee, which makes it $289 there7.

The Advanced program is $399 for three tests across the year24. Add-ons cost extra: fasting insulin is $14, extended thyroid $39, a hormone panel $109 and the Galleri screening $8492.

How does Empirical Health compare with Function Health?

On price, Empirical says it’s cheaper: $190 against Function’s $365 a year, with 100+ biomarkers each10. Those are Empirical’s claims about a rival, so check Function’s own pages before you decide. Empirical says both use the same Quest network. Its page also lists two separate blood draws among the drawbacks people cite for Function10.

Empirical’s Core program is one lab visit, with no doctor video visit12. Its Advanced program adds retests at 3 and 9 months for out-of-range markers, plus a video visit with a doctor24.

Is Empirical Health legit?

Empirical publishes its terms and return policy and names its lab partners, Quest Diagnostics and BioReference356. Its FAQ says results come with a physician-interpreted report3. Its terms say it isn’t a medical group and that independent providers, including 525 Medical Group, P.A., deliver telehealth care6. The pages checked don’t state CLIA or CAP status for the labs138. A used test can’t be refunded, so confirm the price and your state before you pay5.

What does the Empirical Health blood test measure?

The Core program includes ApoB, Lp(a), ApoA1, hs-CRP, a full lipid panel and HbA1c12. It also covers liver and kidney markers, a complete blood count, iron markers, vitamin D, B12 and folate12. Empirical counts 100+ biomarkers, but the list on its homepage has 93 entries. They include 25 urinalysis findings, nine ratios and seven dietary-intake lines1. Fasting insulin, a hormone panel and an extended thyroid panel cost extra2.

The practical details.

Specifications for Empirical Health Heart Health Test
Exact variantCore program: one lab visit with 100+ biomarkers, a written report and app access, $190. The $399 Advanced program adds retests and a doctor video visit
Biomarkers100+ per Empirical. The homepage list has 93 entries, including 25 urinalysis findings, nine ratios, two heart attack risk estimates and seven dietary-intake lines. Empirical doesn't say which entries make up the 100+
Key markersApoB, Lp(a), ApoA1, hs-CRP, a full lipid panel, HbA1c, glucose, TSH with reflex to T4, liver and kidney markers, a complete blood count, an iron panel, vitamin D, B12 and folate
ProgramsCore is $190 for one lab visit with a written report. Advanced is $399 for 3 tests across the year, with retests at 3 and 9 months for out-of-range markers and a video visit with a doctor
Add-onsFasting insulin +$14, PSA +$19, extended thyroid +$39, hormone panel +$109 and Galleri multi-cancer screening +$849, a one-time charge on a separate lab order
Sample collectionBlood draw at one of 2,200+ testing sites: Quest in most of the country, BioReference in New York and New Jersey. Walk-ins are usually possible. No home draw is mentioned
PreparationFasting for 8 to 12 hours is recommended. Empirical suggests a morning appointment and no strenuous exercise the evening before
TurnaroundMost results within 3 to 5 business days of the draw. Complete results usually take 2 to 3 weeks, as the lab finishes each marker
Clinician reviewThe FAQ says results come with a physician-interpreted report, and the locations page says doctor-reviewed results with a personalized care plan. The order page calls the Core output a written report. A video visit with a board-certified doctor is part of the Advanced program
New York and New JerseyThe Core program is $289: the $190 plus a $99 lab fee. Blood is drawn at BioReference, not Quest
Eligibility and paymentUsers must be 18 or older. Empirical says its medical services cover over 30 states and doesn't list them all. The heart health program is cash pay. A separate Medicare-covered care program has only a waitlist page
Refunds and renewalNo refund once a test is used. An unused test can be refunded on request after 30 days. Whether the $190 renews isn't clear: the homepage says one-time and the comparison pages say $190/year
DimensionsNo physical product. It's a lab test with an app and a written report.
MaterialsNot applicable, since there's no hardware. Empirical's order page lists a urinalysis among the baseline markers. It doesn't spell out how the urine sample is collected.

Before you buy

InstallationNothing to install

Nothing to install. You give blood at a lab: Quest in most of the country and BioReference in New York and New Jersey. Empirical says it has 2,200+ testing sites, and you can usually walk in or book a same-day or next-day appointment. Bring a photo ID, since the lab order is sent to the lab electronically. The pages checked don't mention a home draw.

WarrantyNo warranty

No warranty. Under the terms of use, Empirical provides its platform and services "as is", with no warranties of any kind. Empirical doesn't warrant the accuracy, completeness or timeliness of information from the platform. The terms exclude most damages and cap any remaining liability at $500. They say your sole remedy for dissatisfaction is to stop using the platform. Disputes go to binding arbitration, and the terms bar class actions.

ReturnsEmpirical's return policy lets you request a refund if you haven't used…

Empirical's return policy lets you request a refund if you haven't used a test within 30 days of buying it. Once a test is used, it can't be returned or refunded. If an order has the wrong biomarkers, Empirical says it will amend the order at no extra cost. Refund requests go by email to hello@empirical.health. The terms let Empirical refuse or cancel an order. The policy covers lab tests, and the pages checked give no separate rule for the Advanced program.

More about this assessment

Empirical Health's Heart Health Test is a cardiovascular-focused lab test with an app and written report. The Core program costs $190 for one lab visit with 100+ biomarkers, including ApoB, Lp(a) and hs-CRP. Blood is drawn at Quest, or at BioReference in New York and New Jersey, and the price includes app access. New York and New Jersey add a $99 lab fee, which makes the Core program $289 there. The $399 Advanced program adds retests at 3 and 9 months for out-of-range markers, plus a doctor video visit. Empirical's homepage calls the $190 a one-time payment, but its comparison pages print the price as "$190/year". A used test can't be refunded, and Empirical's pages don't state the labs' CLIA or CAP status.

Strengths on paper

  • $190 for 100+ biomarkers in one lab visit, with ApoB, Lp(a) and hs-CRP included
  • Draws at 2,200+ testing sites, with walk-ins usually possible
  • Most results in 3 to 5 business days, per Empirical
  • A physician-interpreted report, per Empirical's FAQ
  • App access is included in the $190, with no separate app fee

Limitations

  • Empirical's pages disagree on whether the $190 is a one-time payment or a yearly price
  • New York and New Jersey add a $99 lab fee, making the Core program $289
  • Retests and the doctor video visit come with the $399 Advanced program
  • Fasting insulin, a hormone panel and extended thyroid markers are paid add-ons
  • A used test can't be refunded, and an unused one can be refunded only after 30 days
  • The 100+ count includes calculated ratios, urinalysis findings and dietary-intake lines, and the homepage list has 93 entries
  • The pages checked don't state the labs' CLIA or CAP status

Running costs.

PLAN YOUR OWNERSHIP COSTS

What will it cost to own?

Change the assumptions to fit your use. Leave an unknown cost blank. Add water, subscriptions, cleaning, shipping and taxes if they apply. Use average operating power, not the maximum rating.

3-year planning total

$190.00

Every field has a value. This is an estimate, not a quote.

Energy component: $0.00

Purchase + installation + years × (annual consumables + annual other) + watts/1000 × hours/day × 365 × years × $/kWh. Annualized allowances, not an exact replacement schedule. Excludes taxes, shipping, finance and resale unless entered.
Replacement parts & cost assumptions

Recorded recurring parts and refills:

  • Advanced program (3 tests across 12 months): $399 every 12 months. Optional. Empirical's order page lists the Advanced program at $399, which it says works out to $133 a test. It adds retests at 3 and 9 months for out-of-range markers and a doctor video visit. It isn't counted in the yearly cost, and the pages checked don't say whether it renews.
  • The purchase is the $190 Core program, which Empirical's homepage calls a one-time payment. Nothing recurring is counted, so the three-year figure is $190 if you test once.
  • Empirical's comparison pages print the same price as "$190/year". If it did renew yearly, three years would cost $570 before tax. No page explains the difference.
  • New York and New Jersey add a $99 lab fee, so the Core program is $289 there. That's left out because it depends on your state.
  • The Advanced program is $399 for three tests across the year, which Empirical says is $133 a test. It's optional, so it's left out.
  • Add-on panels are left out. They run from $14 for fasting insulin to $849 for the Galleri add-on.
  • The test uses no power, so power draw and daily hours are 0.

Evidence & sources.

Are longevity blood tests and biological-age clocks worth it? Our evidence review grades the research as Not supported. That grade is about the claim, not about this product.

  • Manufacturer claimEmpirical Health sells a heart-focused blood test. The Core program is $190 for one lab visit with 100+ biomarkers, a written report and app access. Price, program contents, add-on prices, lab partners and turnaround all come from Empirical's own pages.1479 Not independently verified. The homepage list has 93 entries, fewer than the 100+ headline. Empirical's comparison page also makes claims about Function Health. Those are Empirical's own marketing, not Function's statements.
  • Manufacturer claimEmpirical says blood is drawn at Quest Diagnostics locations, or at BioReference in New York and New Jersey. Its FAQ says results come with a physician-interpreted report. Its terms say Empirical isn't a medical group and that independent providers, including 525 Medical Group, P.A., deliver telehealth care.368 The pages checked don't state CLIA or CAP status for the labs, or name the clinicians who review a Core report. Lab status wasn't checked against CMS or CAP listings.
  • Manufacturer claimEmpirical's homepage calls the $190 Core program a one-time payment, while its comparison pages print the same price as "$190/year". Its terms say a subscription renews automatically unless you cancel, and that Empirical may change subscription prices. Its changelog says the Advanced program launched in November 2025 as a subscription. By April 2026 it was also offered as a one-time package.161012 No page says whether the $190 or the $399 renews. The review treats $190 as a one-time payment, as the homepage does, and lists the conflict as unknown.
  • Published studyA Cochrane review pooled randomized trials of general health checks in adults not selected for disease or risk factors. Health checks had little or no effect on total mortality (RR 1.00, 95% CI 0.97 to 1.03; 11 trials; high certainty). They also had little or no effect on cancer mortality (RR 1.01, 0.92 to 1.12; 8 trials; high certainty). Their effect on cardiovascular mortality was probably little or none (RR 1.05, 0.94 to 1.16; 9 trials; moderate certainty).11 The review included 17 trials, 15 with outcome data on 251,891 participants. The authors concluded that general health checks are unlikely to be beneficial. The trials tested health checks in general, not Empirical's panel, and the pages checked cite no outcome study of the program.
Sources (13)
  1. Empirical Health home page Empirical Health · manufacturer · checked Oct 24, 2026
  2. Empirical Health order page: choose your program Empirical Health · manufacturer · checked Oct 24, 2026
  3. Empirical Health FAQ Empirical Health · manufacturer · checked Oct 24, 2026
  4. Empirical Health 12-Month Advanced Heart Health Program Empirical Health · manufacturer · checked Oct 24, 2026
  5. Empirical Health return policy Empirical Health · manufacturer · checked Oct 24, 2026
  6. Empirical Health Terms of Use (last modified 11/12/2025) Empirical Health · manufacturer · checked Oct 24, 2026
  7. Empirical Health testing locations Empirical Health · manufacturer · checked Oct 24, 2026
  8. Where do I go for my blood draw? (Empirical Health help center) Empirical Health · manufacturer · checked Oct 24, 2026
  9. When will I get my results? (Empirical Health help center) Empirical Health · manufacturer · checked Oct 24, 2026
  10. Empirical Health vs Function Health Empirical Health · manufacturer · checked Oct 24, 2026
  11. General health checks in adults for reducing morbidity and mortality from disease (Krogsbøll, Jørgensen, Gøtzsche; Cochrane Database Syst Rev 2019) Cochrane Database of Systematic Reviews · study · checked Oct 24, 2026
  12. Empirical Health changelog Empirical Health · manufacturer · checked Oct 24, 2026
  13. Empirical Health Medicare-covered cardiovascular care Empirical Health · manufacturer · checked Oct 24, 2026

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About this review. The facts on this page come from manufacturer pages and published studies, checked Oct 24, 2026. The sources are listed above.

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