Tally Health
TallyAge Test
At-home cheek-swab epigenetic age test built on Tally's CheekAge clock
$249
Compare with this one →Our biological-age test pick
TruDiagnosticTruAge Test
Multi-clock epigenetic age report from one finger-prick kit
Source-based analysis, not hands-on testing. Our method
Cofounder of Superhuman Chambers · About the author. General information, not medical advice. No independent clinical review is claimed.
The verdict
TruDiagnostic says one finger prick at home gets you OMICmAge, DunedinPACE, organ-system ages, telomere length and a 12-cell immune report, for $499 a kit. It's for an adult who wants several research measures of aging and won't treat them as a diagnosis. The catch is that sales are final once the kit ships, and OMICmAge's peer-reviewed validation relied partly on TruDiagnostic's own biobank.
The trade-off
Repeat testing gets expensive at $499 a test with no refunds after shipping, the $998 4-test subscription lowers the per-test price but is final sale, and the reproducibility study isn't named.
Model reviewed: Single at-home finger-prick kit, one-time purchase
$499
Check price at TruDiagnostic US price, checked
No affiliate commission on this link. Check the exact variant before buying.
About this price
This is the one-time price on TruDiagnostic's product page and online store ($499.00 USD), before tax and shipping. The regular price shown is the same, so it isn't a sale. TruDiagnostic's online store also lists an "Annual Subscription" plan labeled "Includes 4 tests • Renews annually ($998 billed today)". That works out to about $249.50 a test. The page text describes it only as a 4-test annual subscription "at a discount over one-time purchases". TruDiagnostic doesn't state the shipping cost.
A GOOD FIT FOR
An adult who wants several DNA methylation aging scores, including DunedinPACE, from one sample taken at home, and who'll treat them as research measures rather than a diagnosis.
- You're an adult who wants several research measures of DNA methylation aging, including DunedinPACE, from one finger-prick sample taken at home
- You want a detailed baseline report and can accept that sales are final once the kit ships
THINK TWICE IF
- Anyone looking for a diagnosis or a basis for medical decisions without a clinician
- Anyone who might change their mind after ordering, since there are no refunds once the order ships
- Anyone on a tight budget who wants to retest quarterly: that's $998 a year on the final-sale 4-test subscription, or $1,996 a year at the one-time price
What still needs checking
- Shipping cost
- An itemized list of what's in the kit
- Whether the subscription's 4 kits ship together or across the year
- The subscription's renewal notice and cancellation terms
- How the 98% test-retest reproducibility figure was measured
- Whether the telomere, CRP, IL-6, grip strength and gait speed results are measured directly or estimated from DNA methylation, since the page doesn't say how they're derived from a blood sample
- The OMICmAge paper's competing-interest statement, which wasn't in the article text reviewed, though the paper says the study's samples were shipped to TruDiagnostic for methylation processing
- Whether the "TruAge Test" listing is the "TruAge COMPLETE" test: it promises the age of 11 organ systems and lists SYMPHONYAge among its reports, but the page's science section says organ-system access requires "a new TruAge COMPLETE test or upgrading a previous COMPLETE analysis" and doesn't name this listing
- Whether it's available in every state, including New York
- A minimum age, since the page only says the test is built for adults
- CAP accreditation and FDA status, neither of which the product page mentions
The practical details.
| Exact variant | Single at-home finger-prick kit, one-time purchase |
|---|---|
| Reports | OMICmAge biological age, DunedinPACE pace of aging, 11 organ-system age scores, telomere length, 12-cell immunity, inflammation score (CRP and IL-6), grip strength and gait speed, smoking and alcohol impact scores |
| Biomarkers | 75+ from one sample, per TruDiagnostic |
| Methylation sites | 1,000,000+ DNA methylation sites analyzed, per TruDiagnostic |
| Sample method | A few drops of blood from an at-home finger prick, mailed back in a prepaid USPS envelope |
| Turnaround | 3 to 4 weeks after the lab receives the sample |
| Lab | CLIA-certified, per TruDiagnostic. CMS's provider file lists an active CLIA lab under the TruDiagnostic name in Lexington, Kentucky, with a certificate of compliance that runs to December 28, 2026. The page doesn't mention CAP accreditation or FDA status |
| Reproducibility | 98% test-retest reproducibility, per TruDiagnostic, which doesn't name the study behind the figure |
| Retesting | One-time kit. TruDiagnostic's online store lists an annual subscription with 4 tests for $998, billed up front and renewing every year. It's final sale. TruDiagnostic says many customers retest every 3 to 6 months |
| HSA/FSA | Qualifies for HSA/FSA reimbursement, per TruDiagnostic |
| Dimensions | There's no device. It's a mail-in finger-prick blood collection kit, and TruDiagnostic doesn't give the kit's size or itemize its contents. |
| Materials | Not stated by the manufacturer. The product page says the kit ships with everything you need to test at home, but it doesn't list the contents. |
Before you buy
InstallationNo installation or lab visit
No installation or lab visit. You prick your finger at home, collect a few drops of blood and mail the sample back in the prepaid USPS envelope.
WarrantyNot stated by the manufacturer
Not stated by the manufacturer. TruDiagnostic's refund policy says it sends a free replacement kit when something outside your control goes wrong during delivery or use. Examples include too little blood in the sample or a package lost or damaged in transit. A kit lost or damaged in transit from its warehouse is also replaced free. Only one free replacement is guaranteed.
ReturnsOnce an order ships, all sales are final
Once an order ships, all sales are final. There are no refunds, including for dissatisfaction with results, used or damaged kits, or orders cancelled after shipping. If a first sample fails, TruDiagnostic may send another kit. If both samples fail because of a laboratory error, the policy offers a full refund, including shipping and transaction fees. Annual subscriptions are also final. Kits bought at events or from third-party retailers are non-refundable unless the point of sale says otherwise. The policy is effective as of April 2, 2025.
More about this assessment
The TruAge Test is an at-home DNA methylation test that, TruDiagnostic says, reports 75+ biomarkers from a few drops of finger-prick blood. The report includes an OMICmAge biological age, a DunedinPACE pace of aging, 11 organ-system age scores and telomere length. A single kit costs $499, and a 4-test annual subscription is $998 a year, about $249.50 a test. Results arrive 3 to 4 weeks after the lab receives the sample. The catch is that all sales are final once the kit ships, and annual subscriptions are final too. Researchers say aging biomarkers still lack agreed validation for clinical use.
Strengths on paper
- Combines OMICmAge, DunedinPACE, 11 organ-system ages, telomere length and a 12-cell immune report in one kit
- DunedinPACE's peer-reviewed paper reported test-retest reliability of ICC 0.96 in a research dataset
- OMICmAge's peer-reviewed 2026 Nature Aging paper reported an ICC of 0.998 across 30 replicates
- In the same paper, OMICmAge had a 5-year mortality AUC of 0.892 in a held-out test set
- Finger-prick collection at home and a prepaid USPS return envelope, with no lab visit
- Processed in a CLIA-certified lab, per TruDiagnostic
- One free replacement kit is guaranteed for errors outside your control, such as too little blood or a kit lost or damaged in transit
- A full refund if two samples fail because of lab error
- The annual subscription brings the price down to about $249.50 a test, for 4 tests a year
- HSA/FSA eligible, per TruDiagnostic
Limitations
- $499 per test, with no refunds once the order ships
- One of OMICmAge's two validation cohorts was TruDiagnostic's own biobank
- In the independent Generation Scotland cohort, OMICmAge ranked second to PCGrimAge for 5-year mortality prediction (AUC 0.861 vs 0.870)
- Results take 3 to 4 weeks after the lab receives the sample
- The 98% reproducibility figure isn't tied to a named study
- The $998 subscription is final sale
- The subscription's kit schedule and cancellation terms aren't stated
- The subscription price appears in TruDiagnostic's store listing, not the page text
What it costs to own.
Adjust the assumptions for your use. Missing costs stay unknown.
PLAN YOUR OWNERSHIP COSTS
What will it cost to own?
Change the assumptions to fit your use. Leave an unknown cost blank. Add water, subscriptions, cleaning, shipping and taxes if they apply. Use average operating power, not the maximum rating.
3-year planning total
$499.00Every field has a value. This is an estimate, not a quote.
Energy component: $0.00
Purchase + installation + years × (annual consumables + annual other) + watts/1000 × hours/day × 365 × years × $/kWh. Annualized allowances, not an exact replacement schedule. Excludes taxes, shipping, finance and resale unless entered.Replacement parts & cost assumptions
No scheduled consumable is listed. That does not mean zero maintenance or repair costs.
- The three-year figure covers one $499 kit and nothing recurring, because it's a single test, not a membership. Shipping isn't included, since TruDiagnostic doesn't state the cost.
- Retesting changes the cost. TruDiagnostic says many customers retest every 3 to 6 months. At the $499 one-time price, that's $998 to $1,996 a year. TruDiagnostic's online store lists an annual subscription with 4 tests for $998 a year, about $249.50 a test. That comes to $2,994 over three years if it renews twice. The subscription is final sale, and the page doesn't say when the 4 kits ship or how to cancel.
Evidence & sources.
Are longevity blood tests and biological-age clocks worth it? Our evidence review grades the research as Not supported. That grade is about the claim, not about this product.
- Manufacturer claimTruDiagnostic says samples are processed in a CLIA-certified lab and that TruAge has 98% test-retest reproducibility. It also says its algorithms are validated across more than 50 peer-reviewed publications.17 These are the maker's own statements, though CMS's provider file does list an active CLIA lab under the TruDiagnostic name in Lexington, Kentucky. The page doesn't name the reproducibility study, mention CAP accreditation or give FDA status. It says you don't need a prescription or diagnosis to take the test.
- Published studyDunedinPACE was developed from two decades of decline in 19 organ-system indicators in the Dunedin Study's 1972–1973 birth cohort. It was then tested in five more datasets. The peer-reviewed paper reports excellent test-retest reliability (ICC 0.96). It also reports associations with mortality (hazard ratio 1.26 in the Normative Aging Study and 1.65 in the Framingham Offspring cohort), new chronic disease and disability.4 These are observational associations in research cohorts. They don't show that lowering a DunedinPACE score improves health. The authors write that effect sizes were similar to the GrimAge clock. Several authors are listed as inventors on a Duke University and University of Otago invention, licensed to a commercial entity the paper page doesn't name.
- Published studyOMICmAge, the headline biological age, is described in a peer-reviewed Nature Aging paper (Chen et al., published online February 25, 2026). The authors first built EMRAge, a mortality-risk measure based on routine clinical lab data from about 31,000 Mass General Brigham Biobank participants. They then developed OMICmAge in 3,451 MGB Aging Biobank Cohort participants with multi-omic data (2,762 for training, 689 held out for testing), so it can be estimated from DNA methylation alone. It was validated in the TruDiagnostic Biobank (n = 14,213) and Generation Scotland (n = 18,672). The paper reports an intraclass correlation of 0.998 across 30 replicates. For 5-year mortality, the AUC was 0.892 in the held-out MGB test set and 0.861 in Generation Scotland.5 In Generation Scotland, OMICmAge ranked second to PCGrimAge (5-year AUC 0.870). In the MGB test set, the related DNAmEMRAge scored slightly higher (0.898). The TruDiagnostic Biobank was used to test associations with existing disease. The study's samples were shipped to TruDiagnostic for methylation processing. The authors write that OMICmAge needs additional validation across diverse populations. Mortality AUC measures prediction, not whether changing the score changes outcomes.
- Published studyA 2024 Nature Medicine review by Moqri and colleagues says there's no consensus on how biomarkers of aging should be validated before they're used in the clinic. It says rigorous validation will be critical to moving them into clinical use.3 The review covers omic-based aging biomarkers in general, not TruAge specifically. It describes them as possible predictors of aging-related outcomes and possible surrogate endpoints, not as validated clinical tests.
Sources (7)
- TruAge Test TruDiagnostic · manufacturer · checked Oct 13, 2026
- TruDiagnostic refund policy (effective April 2, 2025) TruDiagnostic · manufacturer · checked Oct 13, 2026
- Validation of biomarkers of aging (Moqri et al., Nature Medicine 2024) Nature Medicine · study · checked Oct 13, 2026
- DunedinPACE, a DNA methylation biomarker of the pace of aging (Belsky et al., eLife 2022) eLife · study · checked Oct 13, 2026
- OMICmAge quantifies biological age by integrating multi-omics with electronic medical records (Chen et al., Nature Aging 2026) Nature Aging · study · checked Oct 13, 2026
- TruAge Test listing on TruDiagnostic's store, including the Annual Subscription plan TruDiagnostic · manufacturer · data file · checked Oct 13, 2026
- Provider of Services File: Clinical Laboratories (record for TruDiagnostic, CLIA 18D2183496) Centers for Medicare & Medicaid Services · regulator · checked Oct 14, 2026
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About this review. The facts on this page come from manufacturer pages, regulator records and published studies, checked Oct 13, 2026. The sources are listed above.
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