BLOOD TEST COMPARISON

Quest Elite Health Profile vs Function Health vs SiPhox Health: one-off, membership or at home

All three sell blood testing you order yourself, at a published price. Quest sells one lab visit with nothing to renew. Function sells a yearly membership with two Quest draws. SiPhox mails a kit for a small sample from your upper arm at home, as often as monthly. We found no evidence that any of these panels improves health.

By Porsche Ma Comparison Updated Oct 13, 2026

The bottom line

Choose Quest’s Elite Health Profile for one broad lab panel with nothing to renew, at $405 a test. Choose Function if you’ll test twice in a year: two Quest draws cost $365 in the first year. Choose SiPhox if you won’t go to a lab, at $124 to start for a smaller at-home panel. None has outcome trials behind it.

Source-based analysis, not hands-on testing. Our method

Cofounder of Superhuman Chambers · About the author. General information, not medical advice. No independent clinical review is claimed.

The products compared

Photo: Quest Diagnostics

Our no-membership pick

Quest Diagnostics Elite Health Profile

$399US price, checked Oct 13, 2026

Check price at Quest Diagnostics Read the review →

Our all-round blood-panel pick

Function Membership

$365 for the first yearUS price, checked Oct 13, 2026

Check price at Function Health Read the review →

SiPhox Health

SiPhox Health Membership

$124US price, checked Oct 13, 2026

Check price at SiPhox Health Read the review →

These links go to each brand’s own store and earn us no commission. Prices are dated US snapshots.

In this article

The three side by side

Quest’s panel covers 85+ markers, and each retest costs $405 again at today’s price¹. Function doesn’t state its renewal price⁵. SiPhox’s kit tests a much smaller panel, with 25 biomarkers on Longevity Essentials¹¹. We found no outcome trials for any of the three^{1, 20}.

Prices are US list prices on each company’s official pages, before tax, checked on October 13, 2026. Every price and product figure is the company’s own. Where a cell says something isn’t stated, we didn’t find it on the pages checked.

Published prices, markers, collection, turnaround, review, availability and purchase terms for Quest Elite Health Profile, Function Health and SiPhox Health, checked Oct 13, 2026
Question	Quest Elite Health Profile	Function Health Membership	SiPhox Health Membership
What you buy	One blood and urine draw at a Quest Patient Service Center. No membership, and nothing renews¹	A yearly membership with two draws: 100+ lab tests at an annual visit, then 60+ in a follow-up 3 to 6 months later^{4, 6}	An at-home kit with one of four included panels: Longevity Essentials, Thyroid Focus, Hormone Focus or Heart & Metabolic. You can switch panels anytime⁹
US price	$399 plus a $6 physician service fee, so $405 a test. No sale price shown¹	$365 for the first year, charged annually. It renews at the then-current price, which Function doesn’t state⁵	$124 to start testing, plus shipping and handling, with no monthly fees. SiPhox doesn’t publish the shipping charge or say whether later kits cost the same^{10, 13}
How often you test	Once per purchase. Quest doesn’t suggest a retest schedule, and each retest costs $405¹	Twice a year, 3 to 6 months apart^{4, 6}	Monthly, quarterly or every 6 months^{9, 10}
Markers	85+, including a CBC, metabolic and cholesterol panels, urinalysis, HbA1c, insulin, hs-CRP, ApoB, thyroid markers, ferritin, vitamin D, B12, folate and testosterone¹	160+ lab tests a year across both visits^{4, 6}	25 biomarkers per test on Longevity Essentials, and SiPhox says upgrades reach up to 62. Counts for the other three panels aren’t stated^9–11
Extras	Height, weight, waist and blood pressure, a health risk survey and a Health Quotient Score from 1 to 100 are included. Home collection costs $79 extra where offered¹	Add-on tests and home or office draws cost extra, with no prices shown. Imaging isn’t included, but members can get an Annual MRI for $999^{4, 6–8}	Swapping in Ultimate 360 costs $125 more, and the GLP Optimization Panel $75 more. On Longevity Essentials, CBC adds $45 and IGF-1 $70, or $100 for both^{9, 11}
How the sample is taken	Blood and urine at one of 2,000+ Quest Patient Service Centers, or at home through Quest Mobile where offered. Fasting 8 to 12 hours is recommended^{1, 3}	A blood draw (about 35 to 85 mL) at one of 2,000+ Quest locations, or at home or work in select areas. Fast for 8 hours^{4, 6, 7}	You take a small sample from your upper arm with the EasyDraw kit, in about 5 minutes with live support. SiPhox says it needs no vein draw or fingerprick, though its Longevity Essentials page also describes a fingerstick. Fasting 8 to 12 hours is strongly recommended^{9–11, 16}
Results	Typically 3 to 5 business days, including processing and clinical review¹	First results typically start arriving within 48 hours of testing. After an at-home draw, Function says results take around 2 weeks^{6, 7}	7 to 10 days, with same-day pickup of samples^{9, 10}
Who reviews results	A provider licensed in your state reviews, approves and orders the test, and may contact you if a result needs attention. You can discuss results with an independent provider at no extra cost^{1, 2}	Clinicians review every result and add a summary and action items, per Function^{4, 6}	SiPhox calls itself a wellness-only service that isn’t meant to diagnose, prevent or treat disease. Its terms say it isn’t a health care provider and doesn’t offer lab review, outside a separate medication-management program^{10, 11, 13}
Lab statements	Quest says it and certain affiliates are CLIA-certified labs. It doesn’t say whether the panel’s assays are FDA-cleared or lab-developed, and doesn’t mention CAP^1–3	Quest is named as the lab partner. CLIA or CAP accreditation isn’t stated. Function says it’s a technology company, not a lab or medical provider^{4–6, 8}	Samples go to a CLIA-certified lab, with CLIA and CAP badges shown. SiPhox doesn’t name the lab^{9, 15}
Who and where	Patients 18 to 100, US only. Collection isn’t available in Arizona, Hawaii or Puerto Rico, and Quest warns that other state rules can block a purchase^{1, 2}	Adults 18+ who aren’t currently pregnant, in 48 states. It isn’t offered yet in Rhode Island, Hawai’i or Puerto Rico. In New York and New Jersey, its terms say the lab may bill some fees to you directly^{5, 6, 8}	Adults 18 and older. Not yet offered in Hawaii or New York^{13, 14}
Insurance and HSA/FSA	Quest doesn’t bill insurance. HSA/FSA accepted^{1, 2}	Function doesn’t bill insurance. Listed as HSA/FSA eligible, subject to your plan^{4, 6}	SiPhox doesn’t accept insurance. HSA/FSA eligible^{9, 17, 18}
Canceling and refunds	Cancel before collection, within 60 days, for a refund minus a $20 fee per order. An unused purchase expires after 60 days and is refunded minus the same fee²	A full refund only within 48 hours of first purchase and before any specimen is collected. Nonrefundable after that^{6, 8}	No refund for a billing period once its kit ships, and kits can’t be returned. You can cancel before a kit ships, or move your next shipment date in your account^{12, 13, 19}
Two draws in one year, known items only	$810 for two panels¹	$365 in the first year⁵	$248 for two kits, if each costs $124, before shipping^{9, 10}
Three years, known items only	$405 if you test once, or $1,215 for one test a year¹	$1,095 if renewal stays at $365 a year, which Function doesn’t promise. Extras aren’t included⁵	$744 at one kit every 6 months, if every kit costs $124. Shipping, upgrades and add-ons aren’t included^{9, 10}
Outcome evidence found	Quest cites no outcome study of this panel. A Cochrane review found general health checks had little or no effect on total mortality^{1, 20}	No trial of the membership found	No trial of SiPhox’s panels found

Which blood test should you get?

These are picks for different needs, not a ranking. The real choice is how you pay and how the blood is taken. You can go to a lab once, go twice a year, or test at home on a schedule.

One broad panel, nothing to renew: Quest Elite Health Profile. $405 buys 85+ markers from one blood and urine visit, including ApoB, insulin and HbA1c, with results typically in 3 to 5 business days¹. The catch: it’s one snapshot, and tracking changes means paying $405 again. Canceling before the draw costs $20, and collection isn’t available in Arizona, Hawaii or Puerto Rico^{1, 2}.
Two draws a year with clinician review: Function Health. $365 covers an annual visit with 100+ lab tests and a 60+ test follow-up at Quest, and clinicians review every result^4–6. The catch: it renews at a price Function doesn’t state, and refunds end 48 hours after purchase or at the first specimen^{5, 8}. Add-on tests, imaging and home draws cost extra. Function doesn’t publish prices for add-on tests or home draws^{4, 6–8}.
Testing at home, as often as monthly: SiPhox Health. $124 to start buys a kit for an upper-arm sample at home, with results in 7 to 10 days^{9, 10}. You pick one of four panels and can switch anytime⁹. The catch: Longevity Essentials covers 25 biomarkers, and reaching 62 costs extra^9–11. SiPhox won’t refund a billing period once the kit ships, and it doesn’t serve Hawaii or New York^{12, 14}.

What a year, and three years, cost

Your first order costs $124 plus shipping at SiPhox, $365 at Function and $405 at Quest^{1, 5, 10}. Function’s price covers two draws, and the others cover one. The panels also differ in size. Quest lists 85+ markers, Function 100+ lab tests at the first visit and SiPhox’s Longevity Essentials 25 biomarkers^{1, 6, 11}.

For two draws in a year, Quest costs $810 and Function $365^{1, 5}. Two SiPhox kits come to $248 before shipping, if each costs $124, which SiPhox doesn’t confirm^{9, 10}. Testing monthly with SiPhox would come to $1,488 a year on the same assumption^{9, 10}.

Over three years, testing once a year with Quest comes to $1,215¹. Function comes to $1,095 if it renews at $365 a year, which it doesn’t promise⁵. SiPhox comes to $744 at one kit every 6 months, before shipping, upgrades and add-ons^{9, 10}.

What the marketing doesn’t settle

Counts aren’t like for like. Quest counts markers, and SiPhox counts biomarkers per panel^{1, 11}. Function mostly counts lab tests, though one of its pages calls the annual panel 100+ biomarkers^{4, 7}. Quest’s package also includes a health risk survey and a Health Quotient Score from 1 to 100¹. Neither is a lab test.

Lab statements are the companies’ own. Quest says it and certain affiliates are CLIA-certified labs, but it doesn’t say whether this panel’s assays are FDA-cleared or lab-developed^1–3. Function’s pages don’t state CLIA or CAP accreditation^{4, 5}. SiPhox says a CLIA-certified lab runs its tests but doesn’t name the lab or the device in its kit^{9, 10, 15}. It says third parties run its mail-in tests in line with lab-developed test rules^{9, 15}.

Outcome evidence is thin for all three. A Cochrane review of randomized trials found general health checks in adults had little or no effect on total mortality (RR 1.00, 95% CI 0.97 to 1.03; 11 trials; high certainty)²⁰. Those trials tested health checks in general, not these panels or at-home kits. Quest cites no outcome study of its panel¹, and we found no trial of Function’s or SiPhox’s.

Sources

Quest Health: Elite Health Profile (18386M) Quest Diagnostics (Quest Health) · manufacturer
Quest Health consumer terms and conditions (last revised January 6, 2026) Quest Diagnostics (Quest Health) · manufacturer
Quest Health home page Quest Diagnostics (Quest Health) · manufacturer
Function Health home page Function Health · manufacturer
Function Health pricing Function Health · manufacturer
Function Health FAQ Function Health · manufacturer
How Function Health works Function Health · manufacturer
Function Health Terms of Service (updated October 7, 2026) Function Health · manufacturer
SiPhox Health pricing SiPhox Health · manufacturer
SiPhox Health home page SiPhox Health · manufacturer
SiPhox Health: Longevity Essentials Program SiPhox Health · manufacturer
SiPhox Health Refund Policy (updated Feb 2, 2026) SiPhox Health · manufacturer
SiPhox Health Terms of Service (last updated June 15, 2026) SiPhox Health · manufacturer
SiPhox Health State Coverage SiPhox Health · manufacturer
SiPhox Health FAQs SiPhox Health · manufacturer
SiPhox Health Support Center: Do I need to fast before taking my test? SiPhox Health · manufacturer
SiPhox Health Support Center: Can I pay using HSA/FSA funds? SiPhox Health · manufacturer
SiPhox Health Support Center: Does SiPhox Health accept insurance? SiPhox Health · manufacturer
SiPhox Health Support Center: Can I receive a refund or delay my shipment? SiPhox Health · manufacturer
General health checks in adults for reducing morbidity and mortality from disease (Krogsbøll, Jørgensen, Gøtzsche) Cochrane Database of Systematic Reviews, 2019 · systematic review

How this was written. Written from the sources listed above, checked Oct 13, 2026. It is general information, not medical advice. Talk to a clinician before acting on anything here if you have a health condition or take medication.

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