SIDE BY SIDE

Compare products.

See prices, running costs, specifications and trade-offs side by side. Choose two to four products of the same type.

Change products

Product 1Product 2Product 3 (optional)Product 4 (optional)

Blood test

Empirical Health Heart Health Test

Core program: one lab visit with 100+ biomarkers, a written report and app access, $190. The $399 Advanced program adds retests and a doctor video visit

$190US price, checked Oct 24, 2026

Heart-focused blood panel with ApoB and Lp(a) in one lab visit

Check price at Empirical Health Full review →

Photo: Quest Diagnostics

Blood test

Quest Diagnostics Elite Health Profile

One-time blood and urine panel (item 18386M), 85+ markers, collected at a Quest Patient Service Center, no membership

$399US price, checked Oct 13, 2026

One-time Quest blood and urine panel of 85+ markers, no membership

Check price at Quest Diagnostics Full review →

Criterion	Empirical Health Heart Health Test	Quest Diagnostics Elite Health Profile
US price	$190Checked Oct 24, 2026 · Price details in the review	$399Checked Oct 13, 2026 · Price details in the review
Three-year ownership estimate	$190 Planning total.	$405 Planning total.
Choose if	An adult who wants ApoB, Lp(a) and a broad panel from one lab visit, paid out of pocket.	You want ApoB, insulin, HbA1c and thyroid markers from one visit, paid once, without joining a membership.
Main trade-off	Its pages disagree on whether $190 is one-time or yearly, and the $399 plan adds retests and a doctor video visit.	It's one draw for $405, so tracking changes over time means paying full price again.
Key specifications	Biomarkers: 100+ per Empirical. The homepage list has 93 entries, including 25 urinalysis findings, nine ratios, two heart attack risk estimates and seven dietary-intake lines. Empirical doesn't say which entries make up the 100+ Key markers: ApoB, Lp(a), ApoA1, hs-CRP, a full lipid panel, HbA1c, glucose, TSH with reflex to T4, liver and kidney markers, a complete blood count, an iron panel, vitamin D, B12 and folate Programs: Core is $190 for one lab visit with a written report. Advanced is $399 for 3 tests across the year, with retests at 3 and 9 months for out-of-range markers and a video visit with a doctor Add-ons: Fasting insulin +$14, PSA +$19, extended thyroid +$39, hormone panel +$109 and Galleri multi-cancer screening +$849, a one-time charge on a separate lab order Sample collection: Blood draw at one of 2,200+ testing sites: Quest in most of the country, BioReference in New York and New Jersey. Walk-ins are usually possible. No home draw is mentioned Preparation: Fasting for 8 to 12 hours is recommended. Empirical suggests a morning appointment and no strenuous exercise the evening before Turnaround: Most results within 3 to 5 business days of the draw. Complete results usually take 2 to 3 weeks, as the lab finishes each marker Clinician review: The FAQ says results come with a physician-interpreted report, and the locations page says doctor-reviewed results with a personalized care plan. The order page calls the Core output a written report. A video visit with a board-certified doctor is part of the Advanced program New York and New Jersey: The Core program is $289: the $190 plus a $99 lab fee. Blood is drawn at BioReference, not Quest Eligibility and payment: Users must be 18 or older. Empirical says its medical services cover over 30 states and doesn't list them all. The heart health program is cash pay. A separate Medicare-covered care program has only a waitlist page Refunds and renewal: No refund once a test is used. An unused test can be refunded on request after 30 days. Whether the $190 renews isn't clear: the homepage says one-time and the comparison pages say $190/year	Markers: 85+, including a CBC, a metabolic panel (CMP), cholesterol panel, urinalysis, glucose, HbA1c, insulin, hs-CRP, ApoB, TSH, free T3, free T4, ferritin, vitamin D, B12, folate and testosterone. Quest says the testosterone test measures total testosterone Also included: Biometrics (height, weight, waist and blood pressure) measured at your appointment, a health risk survey and Quest's Health Quotient Score from 1 to 100 Sample and collection: Blood and urine at one of 2,000+ Quest Patient Service Centers, or at home through Quest Mobile for $79 extra where offered. Quest says collection isn't available in AZ, HI or PR Preparation: Fasting for 8 to 12 hours (water only) is recommended Turnaround: Results typically within 3 to 5 business days of your sample, including processing and clinical review Cost and cancellation: $399 plus a $6 physician service fee per test, with no membership. You can cancel before collection within 60 days and get a refund minus a $20 fee, which includes the provider's fees Doctor involvement: No doctor visit needed to buy. A provider licensed in your state reviews, approves and orders the testing, and may contact you if a result needs medical attention. You can discuss results with an independent provider at no extra cost Eligibility and payment: Buyer 18 or older, US only. Quest's provider won't approve orders for patients over 100. The page warns that state restrictions can block the purchase. Quest doesn't bill insurance or allow reimbursement claims
Exact variant	Core program: one lab visit with 100+ biomarkers, a written report and app access, $190. The $399 Advanced program adds retests and a doctor video visit	One-time blood and urine panel (item 18386M), 85+ markers, collected at a Quest Patient Service Center, no membership
Dimensions	No physical product. It's a lab test with an app and a written report.	No physical product. It's a blood and urine test collected at a Quest location or, where offered, at home.
Installation	Nothing to install. You give blood at a lab: Quest in most of the country and BioReference in New York and New Jersey. Empirical says it has 2,200+ testing sites, and you can usually walk in or book a same-day or next-day appointment. Bring a photo ID, since the lab order is sent to the lab electronically. The pages checked don't mention a home draw.	No installation. You give blood and urine samples at one of 2,000+ Quest Patient Service Centers. Quest Mobile can collect them at home for $79 more where it's offered. Quest says collection isn't available in Arizona, Hawaii or Puerto Rico. It recommends fasting for 8 to 12 hours beforehand, with nothing but water. Quest advises checking with a healthcare provider about any supplements or medications that could affect results. Your height, weight, waist and blood pressure are measured at the appointment.
Materials	Not applicable, since there's no hardware. Empirical's order page lists a urinalysis among the baseline markers. It doesn't spell out how the urine sample is collected.	Not applicable. Quest's labs run the tests, and you can discuss results with an independent healthcare provider at no extra cost.
Warranty	No warranty. Under the terms of use, Empirical provides its platform and services "as is", with no warranties of any kind. Empirical doesn't warrant the accuracy, completeness or timeliness of information from the platform. The terms exclude most damages and cap any remaining liability at $500. They say your sole remedy for dissatisfaction is to stop using the platform. Disputes go to binding arbitration, and the terms bar class actions.	No warranty. Quest's consumer terms provide its services "as is" and "as available", without warranty of any kind. They cap Quest's liability at what you paid. They also say the results aren't intended to diagnose or treat disease.
Returns	Empirical's return policy lets you request a refund if you haven't used a test within 30 days of buying it. Once a test is used, it can't be returned or refunded. If an order has the wrong biomarkers, Empirical says it will amend the order at no extra cost. Refund requests go by email to hello@empirical.health. The terms let Empirical refuse or cancel an order. The policy covers lab tests, and the pages checked give no separate rule for the Advanced program.	Quest's consumer terms let you cancel a test collected at a Quest location any time before collection, within 60 days of purchase. You get the purchase price back minus a $20 fee per order. Quest says that fee includes the provider's fees and its own administrative fees. If you don't give a sample within 60 days, the purchase expires and Quest refunds it automatically, minus the same $20. In some states, taxes aren't refunded either.
Unresolved questions	Whether the $190 Core program renews, since the homepage says one-time and the comparison pages say $190/year How long the included Empirical Pro app access lasts Whether the $399 Advanced program renews after 12 months, since Empirical's changelog first called it a subscription Which states can order, since the FAQ says over 30 and the locations page names 22 and mentions New Jersey Whether the $99 New York and New Jersey lab fee also applies to the Advanced program Which entries make up the 100+ biomarker count, since the homepage list has 93 How the urinalysis sample is collected, which the pages checked don't spell out The price of a standalone retest for Core buyers Who reviews a Core report, and how a doctor follows up on an abnormal result Whether the Quest and BioReference labs hold CLIA or CAP status for these tests, which the pages checked don't state Whether a home blood draw is offered, since the pages checked don't mention one Whether Empirical's Medicare ACCESS care program is live, since its page still says spots open in July 2026 Whether any regulator has acted against Empirical. A web search found nothing, but FDA, FTC and state databases weren't searched	Which states other than Arizona, Hawaii and Puerto Rico block the purchase The name of the provider group that reviews and approves orders Whether a cancellation refund includes the $6 physician fee. The terms call that fee non-refundable but also say the $20 cancellation fee includes the provider's fees Whether the $79 Quest Mobile fee is refundable, which the terms don't say Whether the panel's assays are FDA-cleared or lab-developed, which Quest doesn't say Whether Quest's labs hold CAP accreditation, which Quest doesn't mention

These comparisons use published specifications, not head-to-head tests. Prices and terms are dated. Unknown costs are not zero. Check the exact variant before you buy.